01306nas a2200181 4500008004100000245009600041210006900137300001300206490000800219520069800227100001900925700002500944700002300969700002100992700002201013700002301035856006601058 2023 eng d00aFlutter instability in solids and structures, with a view on biomechanics and metamaterials0 aFlutter instability in solids and structures with a view on biom a202305230 v4793 aThe phenomenon of oscillatory instability called ‘flutter’ was observed in aeroelasticity and rotor dynamics about a century ago. Driven by a series of applications involving non-conservative elasticity theory at different physical scales, ranging from nanomechanics to the mechanics of large space structures and including biomechanical problems of motility and growth, research on flutter is experiencing a new renaissance. A review is presented of the most notable applications and recent advances in fundamentals, both theoretical and experimental aspects, of flutter instability and Hopf bifurcation. Open problems, research gaps and new perspectives for investigations are indicated.1 aBigoni, Davide1 aDal Corso, Francesco1 aKirillov, Oleg, N.1 aMisseroni, Diego1 aNoselli, Giovanni1 aPiccolroaz, Andrea uhttps://royalsocietypublishing.org/doi/10.1098/rspa.2023.052302214nas a2200145 4500008004100000245011100041210006900152300001100221490000800232520168500240100002601925700002301951700002201974856007201996 2023 eng d00aNonreciprocal oscillations of polyelectrolyte gel filaments subject to a steady and uniform electric field0 aNonreciprocal oscillations of polyelectrolyte gel filaments subj a1052250 v1733 aSoft actuators typically require time-varying or spatially modulated control to be operationally effective. The scope of the present paper is to show, theoretically and experimentally, that a natural way to overcome this limitation is to exploit mechanical instabilities. We report experiments on active filaments of polyelectrolyte (PE) gels subject to a steady and uniform electric field. A large enough intensity of the field initiates the motion of the active filaments, leading to periodic oscillations. We develop a mathematical model based on morphoelasticity theory for PE gel filaments beating in a viscous fluid, and carry out the stability analysis of the governing equations to show the emergence of flutter and divergence instabilities for suitable values of the system’s parameters. We confirm the results of the stability analysis with numerical simulations for the nonlinear equations of motion to show that such instabilities may lead to periodic self-sustained oscillations, in agreement with experiments. The key mechanism that underlies such behaviour is the capability of the filament to undergo active shape changes depending on its local orientation relative to the external electric field, in striking similarity with gravitropism, the mechanism that drives shape changes in plants via differential growth induced by gravity. Interestingly, the resulting oscillations are nonreciprocal in nature, and hence able to generate thrust and directed flow at low Reynolds number. The exploitation of mechanical instabilities in soft actuators represents a new avenue for the advancement in engineering design in fields such as micro-robotics and micro-fluidics.1 aCicconofri, Giancarlo1 aDamioli, Valentina1 aNoselli, Giovanni uhttps://www.sciencedirect.com/science/article/pii/S002250962300029701815nas a2200145 4500008004100000245005800041210005800099300001300157490000800170520135300178100001901531700002201550700002701572856007001599 2022 eng d00aOptimal design of planar shapes with active materials0 aOptimal design of planar shapes with active materials a202202560 v4783 a
Active materials have emerged as valuable candidates for shape morphing applications, where a body reconfiguration is achieved upon triggering its active response. Given a desired shape change, a natural question is to compare different morphing mechanisms to select the most effective one with respect to an optimality criterion. We introduce an optimal control problem to determine the active strains suitable to attain a target equilibrium shape while minimizing the complexity of the activation. Specifically, we discuss the planar morphing of active, hyperelastic bodies in the absence of external forces and exploit the notion of target metric to encompass a broad set of active materials in a unifying approach. For the case of affine shape changes, we derive explicit conditions on the body reference configuration for the optimality of homogeneous target metrics. More complex shape changes are analysed via numerical simulations to explore the impact on optimal solutions of different objective functionals inspired by features of existing materials. We show how stresses arising from incompatibilities contribute to reduce the complexity of the controls. We believe that our approach may be exploited for the optimal design of active systems and may contribute to gather insight into the morphing strategies of biological systems.
1 aAndrini, Dario1 aNoselli, Giovanni1 aLucantonio, Alessandro uhttps://royalsocietypublishing.org/doi/abs/10.1098/rspa.2022.025601203nas a2200133 4500008004100000245007700041210006900118490000800187520076200195100002500957700002200982700002201004856004301026 2021 eng d00aNutations in growing plant shoots as a morphoelastic flutter instability0 aNutations in growing plant shoots as a morphoelastic flutter ins0 v3793 aGrowing plant shoots exhibit spontaneous oscillations that Darwin observed, and termed "circumnutations". Recently, they have received renewed attention for the design and optimal actuation of bioinspired robotic devices. We discuss a possible interpretation of these spontaneous oscillations as a Hopf-type bifurcation in a growing morphoelastic rod. Using a three-dimensional model and numerical simulations, we analyse the salient features of this flutter-like phenomenon (e.g. the characteristic period of the oscillations) and their dependence on the model details (in particular, the impact of choosing different growth models) finding that, overall, these features are robust with respect to changes in the details of the growth model adopted.
1 aAgostinelli, Daniele1 aNoselli, Giovanni1 aDeSimone, Antonio uhttps://doi.org/10.1098/rsta.2020.011601749nas a2200157 4500008004100000022001400041245010700055210006900162260003400231490000700265520118500272100002501457700002201482700002201504856006501526 2021 eng d a1664-462X00aNutations in plant shoots: Endogenous and exogenous factors in the presence of mechanical deformations0 aNutations in plant shoots Endogenous and exogenous factors in th bCold Spring Harbor Laboratory0 v123 aWe present a three-dimensional morphoelastic rod model capable to describe the morphogenesis of growing plant shoots driven by differential growth. We discuss the evolution laws for endogenous oscillators, straightening mechanisms, and reorientations to directional cues, such as gravitropic reactions governed by the avalanche dynamics of statoliths. We use this model to investigate the role of elastic deflections due to gravity loading in circumnutating plant shoots. We show that, in the absence of endogenous cues, pendular and circular oscillations arise as a critical length is attained, thus suggesting the occurrence of an instability triggered by exogenous factors. When also oscillations due to endogenous cues are present, their weight relative to those associated with the instability varies in time as the shoot length and other biomechanical properties change. Thanks to the simultaneous occurrence of these two oscillatory mechanisms, we are able to reproduce a variety of complex behaviors, including trochoid-like patterns, which evolve into circular orbits as the shoot length increases, and the amplitude of the exogenous oscillations becomes dominant.
1 aAgostinelli, Daniele1 aDeSimone, Antonio1 aNoselli, Giovanni uhttps://www.frontiersin.org/article/10.3389/fpls.2021.60800502335nas a2200325 4500008004100000022001400041245014400055210006900199300000800268490000600276520131600282653001801598653002401616653001801640653002301658653001601681653002401697653002501721653002501746100002501771700002101796700002301817700002201840700002101862700002501883700002201908700001701930700001901947856004301966 2020 eng d a2640-350100aMicroMotility: State of the art, recent accomplishments and perspectives on the mathematical modeling of bio-motility at microscopic scales0 aMicroMotility State of the art recent accomplishments and perspe a2300 v23 aMathematical modeling and quantitative study of biological motility (in particular, of motility at microscopic scales) is producing new biophysical insight and is offering opportunities for new discoveries at the level of both fundamental science and technology. These range from the explanation of how complex behavior at the level of a single organism emerges from body architecture, to the understanding of collective phenomena in groups of organisms and tissues, and of how these forms of swarm intelligence can be controlled and harnessed in engineering applications, to the elucidation of processes of fundamental biological relevance at the cellular and sub-cellular level. In this paper, some of the most exciting new developments in the fields of locomotion of unicellular organisms, of soft adhesive locomotion across scales, of the study of pore translocation properties of knotted DNA, of the development of synthetic active solid sheets, of the mechanics of the unjamming transition in dense cell collectives, of the mechanics of cell sheet folding in volvocalean algae, and of the self-propulsion of topological defects in active matter are discussed. For each of these topics, we provide a brief state of the art, an example of recent achievements, and some directions for future research.
10aactive matter10aadhesive locomotion10acell motility10acell sheet folding10aknotted DNA10atopological defects10aunicellular swimmers10aunjamming transition1 aAgostinelli, Daniele1 aCerbino, Roberto1 aDel Alamo, Juan, C1 aDeSimone, Antonio1 aHöhn, Stephanie1 aMicheletti, Cristian1 aNoselli, Giovanni1 aSharon, Eran1 aYeomans, Julia uhttp://dx.doi.org/10.3934/mine.202001101464nas a2200157 4500008004100000022001400041245007900055210006900134260000700203490000700210520098300217100001901200700002701219700002201246856003801268 2020 eng d a0021-893600aA Theoretical Study on the Transient Morphing of Linear Poroelastic Plates0 aTheoretical Study on the Transient Morphing of Linear Poroelasti c120 v883 aBased on their shape-shifting capabilities, soft active materials have enabled new possibilities for the engineering of sensing and actuation devices. While the relation between active strains and emergent equilibrium shapes has been fully characterized, the transient morphing of thin structures is a rather unexplored topic. Here, we focus on polymer gel plates and derive a reduced linear model to study their time-dependent response to changes in the fluid environment. We show that independent control of stretching and bending deformations in stress-free conditions allows to realize spherical shapes with prescribed geometry of the mid-plane. Furthermore, we demonstrate that tensile (compressive) membrane stresses delay (accelerate) swelling-induced shape transitions compared to the stress-free evolution. We believe that these effects should be considered for the accurate design of smart systems and may contribute to explain the complexity of natural shapes.
1 aAndrini, Dario1 aLucantonio, Alessandro1 aNoselli, Giovanni uhttps://doi.org/10.1115/1.404880602026nas a2200205 4500008004100000022001400041245009500055210006900150300001100219520136500230653002001595653002401615653001701639653002101656100002501677700002701702700002201729700002201751856004701773 2019 eng d a0022-509600aNutations in growing plant shoots: The role of elastic deformations due to gravity loading0 aNutations in growing plant shoots The role of elastic deformatio a1037023 aThe effect of elastic deformations induced by gravity loading on the active circumnutation movements of growing plant shoots is investigated. We consider first a discrete model (a gravitropic spring-pendulum system) and then a continuous rod model which is analyzed both analytically (under the assumption of small deformations) and numerically (in the large deformation regime). We find that, for a choice of material parameters consistent with values reported in the available literature on plant shoots, rods of sufficient length may exhibit lateral oscillations of increasing amplitude, which eventually converge to limit cycles. This behavior strongly suggests the occurrence of a Hopf bifurcation, just as for the gravitropic spring-pendulum system, for which this result is rigorously established. At least in this restricted set of material parameters, our analysis supports a view of Darwin’s circumnutations as a biological analogue to structural systems exhibiting flutter instabilities, i.e., spontaneous oscillations away from equilibrium configurations driven by non-conservative loads. Here, in the context of nutation movements of growing plant shoots, the energy needed to sustain oscillations is continuously supplied to the system by the internal biochemical machinery presiding the capability of plants to maintain a vertical pose.
10aCircumnutations10aFlutter instability10aGravitropism10aHopf bifurcation1 aAgostinelli, Daniele1 aLucantonio, Alessandro1 aNoselli, Giovanni1 aDeSimone, Antonio uhttps://doi.org/10.1016/j.jmps.2019.10370201778nas a2200157 4500008004100000245009800041210006900139300001400208490000700222520126400229100002201493700001801515700001901533700002201552856004601574 2019 eng d00aSwimming Euglena respond to confinement with a behavioural change enabling effective crawling0 aSwimming Euglena respond to confinement with a behavioural chang a496–5020 v153 aSome euglenids, a family of aquatic unicellular organisms, can develop highly concerted, large-amplitude peristaltic body deformations. This remarkable behaviour has been known for centuries. Yet, its function remains controversial, and is even viewed as a functionless ancestral vestige. Here, by examining swimming Euglena gracilis in environments of controlled crowding and geometry, we show that this behaviour is triggered by confinement. Under these conditions, it allows cells to switch from unviable flagellar swimming to a new and highly robust mode of fast crawling, which can deal with extreme geometric confinement and turn both frictional and hydraulic resistance into propulsive forces. To understand how a single cell can control such an adaptable and robust mode of locomotion, we developed a computational model of the motile apparatus of Euglena cells consisting of an active striated cell envelope. Our modelling shows that gait adaptability does not require specific mechanosensitive feedback but instead can be explained by the mechanical self-regulation of an elastic and extended motor system. Our study thus identifies a locomotory function and the operating principles of the adaptable peristaltic body deformation of Euglena cells.1 aNoselli, Giovanni1 aBeran, Alfred1 aArroyo, Marino1 aDeSimone, Antonio uhttps://doi.org/10.1038/s41567-019-0425-801712nas a2200229 4500008004100000022001400041245010200055210006900157300001200226490000800238520097600246653001601222653002001238653001601258653002201274100001601296700002701312700002701339700002201366700002201388856007201410 2018 eng d a0020-740300aSpontaneous morphing of equibiaxially pre-stretched elastic bilayers: The role of sample geometry0 aSpontaneous morphing of equibiaxially prestretched elastic bilay a481-4860 v1493 aAn elastic bilayer, consisting of an equibiaxially pre-stretched sheet bonded to a stress-free one, spontaneously morphs into curved shapes in the absence of external loads or constraints. Using experiments and numerical simulations, we explore the role of geometry for square and rectangular samples in determining the equilibrium shape of the system, for a fixed pre-stretch. We classify the observed shapes over a wide range of aspect ratios according to their curvatures and compare measured and computed values, which show good agreement. In particular, as the bilayer becomes thinner, a bifurcation of the principal curvatures occurs, which separates two scaling regimes for the energy of the system. We characterize the transition between these two regimes and show the peculiar features that distinguish square from rectangular samples. The results for our model bilayer system may help explaining morphing in more complex systems made of active materials.
10aBifurcation10aElastic bilayer10aPre-stretch10aShape programming1 aCaruso, Noe1 aCvetković, Aleksandar1 aLucantonio, Alessandro1 aNoselli, Giovanni1 aDeSimone, Antonio uhttps://www.sciencedirect.com/science/article/pii/S002074031731176102261nas a2200169 4500008004100000245010000041210006900141300001600210490000800226520169900234100002401933700002601957700001801983700002202001700002202023856004602045 2017 eng d00aKinematics of flagellar swimming in Euglena gracilis: Helical trajectories and flagellar shapes0 aKinematics of flagellar swimming in Euglena gracilis Helical tra a13085-130900 v1143 aActive flagella provide the propulsion mechanism for a large variety of swimming eukaryotic microorganisms, from protists to sperm cells. Planar and helical beating patterns of these structures are recurrent and widely studied. The fast spinning motion of the locomotory flagellum of the alga Euglena gracilis constitutes a remarkable exception to these patterns. We report a quantitative description of the 3D flagellar beating in swimming E. gracilis. Given their complexity, these shapes cannot be directly imaged with current microscopy techniques. We show how to overcome these limitations by developing a method to reconstruct in full the 3D kinematics of the cell from conventional 2D microscopy images, based on the exact characterization of the helical motion of the cell body.The flagellar swimming of euglenids, which are propelled by a single anterior flagellum, is characterized by a generalized helical motion. The 3D nature of this swimming motion, which lacks some of the symmetries enjoyed by more common model systems, and the complex flagellar beating shapes that power it make its quantitative description challenging. In this work, we provide a quantitative, 3D, highly resolved reconstruction of the swimming trajectories and flagellar shapes of specimens of Euglena gracilis. We achieved this task by using high-speed 2D image recordings taken with a conventional inverted microscope combined with a precise characterization of the helical motion of the cell body to lift the 2D data to 3D trajectories. The propulsion mechanism is discussed. Our results constitute a basis for future biophysical research on a relatively unexplored type of eukaryotic flagellar movement.1 aRossi, Massimiliano1 aCicconofri, Giancarlo1 aBeran, Alfred1 aNoselli, Giovanni1 aDeSimone, Antonio uhttps://www.pnas.org/content/114/50/1308501765nas a2200217 4500008004100000022001400041245005300055210005300108300001400161490000700175520110000182653002201282653002501304653002801329653003001357653002701387100002201414700001801436700002201454856007101476 2015 eng d a0022-509600aLiquid crystal elastomer strips as soft crawlers0 aLiquid crystal elastomer strips as soft crawlers a254 - 2720 v843 aIn this paper, we speculate on a possible application of Liquid Crystal Elastomers to the field of soft robotics. In particular, we study a concept for limbless locomotion that is amenable to miniaturisation. For this purpose, we formulate and solve the evolution equations for a strip of nematic elastomer, subject to directional frictional interactions with a flat solid substrate, and cyclically actuated by a spatially uniform, time-periodic stimulus (e.g., temperature change). The presence of frictional forces that are sensitive to the direction of sliding transforms reciprocal, ‘breathing-like’ deformations into directed forward motion. We derive formulas quantifying this motion in the case of distributed friction, by solving a differential inclusion for the displacement field. The simpler case of concentrated frictional interactions at the two ends of the strip is also solved, in order to provide a benchmark to compare the continuously distributed case with a finite-dimensional benchmark. We also provide explicit formulas for the axial force along the crawler body.
10aCrawling motility10aDirectional surfaces10aFrictional interactions10aLiquid crystal elastomers10aSoft biomimetic robots1 aDeSimone, Antonio1 aGidoni, Paolo1 aNoselli, Giovanni uhttp://www.sciencedirect.com/science/article/pii/S002250961530043001733nas a2200217 4500008004100000022001400041245003700055210003700092300001200129490000700141520111900148653002901267653001901296653002201315653002501337653002001362100001801382700002201400700002201422856007101444 2014 eng d a0020-746200aCrawling on directional surfaces0 aCrawling on directional surfaces a65 - 730 v613 aIn this paper we study crawling locomotion based on directional frictional interactions, namely, frictional forces that are sensitive to the sign of the sliding velocity. Surface interactions of this type are common in biology, where they arise from the presence of inclined hairs or scales at the crawler/substrate interface, leading to low resistance when sliding ‘along the grain’, and high resistance when sliding ‘against the grain’. This asymmetry can be exploited for locomotion, in a way analogous to what is done in cross-country skiing (classic style, diagonal stride). We focus on a model system, namely, a continuous one-dimensional crawler and provide a detailed study of the motion resulting from several strategies of shape change. In particular, we provide explicit formulae for the displacements attainable with reciprocal extensions and contractions (breathing), or through the propagation of extension or contraction waves. We believe that our results will prove particularly helpful for the study of biological crawling motility and for the design of bio-mimetic crawling robots.
10aBio-mimetic micro-robots10aCell migration10aCrawling motility10aDirectional surfaces10aSelf-propulsion1 aGidoni, Paolo1 aNoselli, Giovanni1 aDeSimone, Antonio uhttp://www.sciencedirect.com/science/article/pii/S002074621400021301213nas a2200145 4500008004100000245011200041210006900153260001300222520069800235653001900933100002200952700002000974700002200994856005101016 2014 en d00aDiscrete one-dimensional crawlers on viscous substrates: achievable net displacements and their energy cost0 aDiscrete onedimensional crawlers on viscous substrates achievabl bElsevier3 aWe study model one-dimensional crawlers, namely, model mechanical systems that can achieve self-propulsion by controlled shape changes of their body (extension or contraction of portions of the body), thanks to frictional interactions with a rigid substrate. We evaluate the achievable net displacement and the related energetic cost for self-propulsion by discrete crawlers (i.e., whose body is made of a discrete number of contractile or extensile segments) moving on substrates with either a Newtonian (linear) or a Bingham-type (stick-slip) rheology. Our analysis is aimed at constructing the basic building blocks towards an integrative, multi-scale description of crawling cell motility.10aCell migration1 aNoselli, Giovanni1 aTatone, Amabile1 aDeSimone, Antonio uhttp://urania.sissa.it/xmlui/handle/1963/3444901083nas a2200121 4500008004100000245012700041210006900168260002900237520052100266100002200787700002200809856013000831 2014 en d00aA robotic crawler exploiting directional frictional interactions: experiments, numerics, and derivation of a reduced model0 arobotic crawler exploiting directional frictional interactions e bRoyal Society Publishing3 aWe present experimental and numerical results for a model crawler which is able to extract net positional changes from reciprocal shape changes, i.e. ‘breathing-like’ deformations, thanks to directional, frictional interactions with a textured solid substrate, mediated by flexible inclined feet. We also present a simple reduced model that captures the essential features of the kinematics and energetics of the gait, and compare its predictions with the results from experiments and from numerical simulations.1 aNoselli, Giovanni1 aDeSimone, Antonio uhttps://www.math.sissa.it/publication/robotic-crawler-exploiting-directional-frictional-interactions-experiments-numerics-and01071nas a2200145 4500008004100000245006700041210006600108260001300174520054900187100002200736700002400758700002200782700002000804856010100824 2013 en d00aCrawlers in viscous environments: linear vs nonlinear rheology0 aCrawlers in viscous environments linear vs nonlinear rheology bElsevier3 aWe study model self-propelled crawlers which derive their propulsive capabilities from the tangential resistance to motion offered by the environment. Two types of relationships between tangential forces and slip velocities are considered: a linear, Newtonian one and a nonlinear one of Bingham-type. Different behaviors result from the two different rheologies. These differences and their implications in terms of motility performance are discussed. Our aim is to develop new tools and insight for future studies of cell motility by crawling.1 aDeSimone, Antonio1 aGuarnieri, Federica1 aNoselli, Giovanni1 aTatone, Amabile uhttps://www.math.sissa.it/publication/crawlers-viscous-environments-linear-vs-nonlinear-rheology