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Some mathematical models for flagellar activation mechanisms

TitleSome mathematical models for flagellar activation mechanisms
Publication TypeJournal Article
Year of Publication2025
AuthorsAlouges, F, Anello, I, DeSimone, A, Lefebvre-Lepot, A, Levillain, J
JournalMathematical Models and Methods in Applied Sciences
Pagination1-30
Abstract

This paper focuses on studying a model for dyneins, cytoskeletal motor proteins responsible for axonemal activity. The model is a coupled system of partial differential equations inspired by [F. Jülicher and J. Prost, Cooperative molecular motors, Phys. Rev. Lett. 75 (1995) 2618–2621; F. Jülicher and J. Prost, Molecular motors: From individual to collective behavior, Prog. Theor. Phys. Suppl. 130 (1998) 9–16] and incorporating two rows of molecular motors between microtubules filaments. Existence and uniqueness of a solution are proved, together with the presence of a supercritical Hopf bifurcation. Additionally, numerical simulations are provided to illustrate the theoretical results. A brief study on the generalization to N-rows is also included.

URLhttps://doi.org/10.1142/S0218202525500423
DOI10.1142/S0218202525500423

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