@article {2006,
	title = {An estimation of the controllability time for single-input systems on compact Lie Groups},
	journal = {ESAIM Control Optim. Calc. Var. 12 (2006) 409-441},
	year = {2006},
	abstract = {Geometric control theory and Riemannian techniques are used to describe the reachable set at time t of left invariant single-input control systems on semi-simple compact Lie groups and to estimate the minimal time needed to reach any point from identity. This method provides an effective way to give an upper and a lower bound for the minimal time needed to transfer a controlled quantum system with a drift from a given initial position to a given final position. The bounds include diameters of the flag manifolds; the latter are also explicitly computed in the paper.},
	doi = {10.1051/cocv:2006007},
	url = {http://hdl.handle.net/1963/2135},
	author = {Andrei A. Agrachev and Thomas Chambrion}
}
@article {2006,
	title = {Experimental and modeling studies of desensitization of P2X3 receptors.},
	journal = {Molecular pharmacology. 2006 Jul; 70(1):373-82},
	number = {PMID:16627751;},
	year = {2006},
	publisher = {the American Society for Pharmacology and Experimental Therapeutics},
	abstract = {The function of ATP-activated P2X3 receptors involved in pain sensation is modulated by desensitization, a phenomenon poorly understood. The present study used patch-clamp recording from cultured rat or mouse sensory neurons and kinetic modeling to clarify the properties of P2X3 receptor desensitization. Two types of desensitization were observed, a fast process (t1/2 = 50 ms; 10 microM ATP) following the inward current evoked by micromolar agonist concentrations, and a slow process (t1/2 = 35 s; 10 nM ATP) that inhibited receptors without activating them. We termed the latter high-affinity desensitization (HAD). Recovery from fast desensitization or HAD was slow and agonist-dependent. When comparing several agonists, there was analogous ranking order for agonist potency, rate of desensitization and HAD effectiveness, with 2-methylthioadenosine triphosphate the strongest and beta,gamma-methylene-ATP the weakest. HAD was less developed with recombinant (ATP IC50 = 390 nM) than native P2X3 receptors (IC50 = 2.3 nM). HAD could also be induced by nanomolar ATP when receptors seemed to be nondesensitized, indicating that resting receptors could express high-affinity binding sites. Desensitization properties were well accounted for by a cyclic model in which receptors could be desensitized from either open or closed states. Recovery was assumed to be a multistate process with distinct kinetics dependent on the agonist-dependent dissociation rate from desensitized receptors. Thus, the combination of agonist-specific mechanisms such as desensitization onset, HAD, and resensitization could shape responsiveness of sensory neurons to P2X3 receptor agonists. By using subthreshold concentrations of an HAD-potent agonist, it might be possible to generate sustained inhibition of P2X3 receptors for controlling chronic pain.},
	doi = {10.1124/mol.106.023564},
	url = {http://hdl.handle.net/1963/4974},
	author = {Elena Sokolova and Andrei Skorinkin and Igor Moiseev and Andrei A. Agrachev and Andrea Nistri and Rashid Giniatullin}
}
