TY - JOUR T1 - Discrete one-dimensional crawlers on viscous substrates: achievable net displacements and their energy cost Y1 - 2014 A1 - Giovanni Noselli A1 - Amabile Tatone A1 - Antonio DeSimone KW - Cell migration AB - We study model one-dimensional crawlers, namely, model mechanical systems that can achieve self-propulsion by controlled shape changes of their body (extension or contraction of portions of the body), thanks to frictional interactions with a rigid substrate. We evaluate the achievable net displacement and the related energetic cost for self-propulsion by discrete crawlers (i.e., whose body is made of a discrete number of contractile or extensile segments) moving on substrates with either a Newtonian (linear) or a Bingham-type (stick-slip) rheology. Our analysis is aimed at constructing the basic building blocks towards an integrative, multi-scale description of crawling cell motility. PB - Elsevier UR - http://urania.sissa.it/xmlui/handle/1963/34449 U1 - 34591 U2 - Mathematics ER -