TY - RPRT T1 - A fast virtual surgery platform for many scenarios haemodynamics of patient-specific coronary artery bypass grafts Y1 - 2016 A1 - F. Ballarin A1 - Elena Faggiano A1 - Andrea Manzoni A1 - Gianluigi Rozza A1 - Alfio Quarteroni A1 - Sonia Ippolito A1 - Roberto Scrofani A1 - Carlo Antona AB - A fast computational framework is devised to the study of several configurations of patient-specific coronary artery bypass grafts. This is especially useful to perform a sensitivity analysis of the haemodynamics for different flow conditions occurring in native coronary arteries and bypass grafts, the investigation of the progression of the coronary artery disease and the choice of the most appropriate surgical procedure. A complete pipeline, from the acquisition of patientspecific medical images to fast parametrized computational simulations, is proposed. Complex surgical configurations employed in the clinical practice, such as Y-grafts and sequential grafts, are studied. A virtual surgery platform based on model reduction of unsteady Navier Stokes equations for blood dynamics is proposed to carry out sensitivity analyses in a very rapid and reliable way. A specialized geometrical parametrization is employed to compare the effect of stenosis and anastomosis variation on the outcome of the surgery in several relevant cases. PB - Submitted UR - http://urania.sissa.it/xmlui/handle/1963/35240 U1 - 35545 U2 - Mathematics U4 - 1 U5 - MAT/08 ER -