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Abstraction of Markov Population Dynamics via Generative Adversarial Nets

Francesca Cairoli
University of Trieste
Friday, February 5, 2021 - 11:00
Zoom Meeting

Markov Population Models are a widespread formalism used to model the dynamics of complex systems, with applications in Systems Biology and many other fields. The associated Markov stochastic process in continuous time is often analyzed by simulation, which can be costly for large or stiff systems, particularly when a massive number of simulations have to be performed (e.g. in a multi-scale model). A strategy to reduce computational load is to abstract the population model, replacing it with a simpler stochastic model, faster to simulate. Here we pursue this idea constructing a generator capable of producing stochastic trajectories in continuous space and discrete time. This generator is learned automatically from simulations of the original model in a Generative Adversarial setting, meaning we explore the use of Wasserstain GANs, which are state of the art generative models.

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